Mailand group publishes in Science

From University of Copenhagen's press release of 8 May 2015:

Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

The Mailand group at Novo Nordisk Foundation Center for Protein Research (CPR) publishes article in this week's edition of Science on enabling mapping of more than one protein at a time, when proteins repair damaged DNA. The discovery will help researchers speed up the process of developing improved and more gentle cancer treatments.

Niels Mailand on the recent discovery: “We get a much clearer and more general picture of the reparatory process, i.e. where previously, we were only able to see one piece of the puzzle at a time, we are now able to see the entire puzzle. And this makes it a lot easier to see what is going on, and then work from there. The better we understand these processes, the better and gentler cancer treatments we can develop”.

CPR Authors: Godelieve Smeenk, Rebecca K. Hansen, Yasuyoshi Oka, Simon Bekker-Jensen, Niels Mailand, Matthias Mann

Full title: Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links