SignalP: The Evolution of a Web Server
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
SignalP ( https://services.healthtech.dtu.dk/services/SignalP-6.0/ ) is a very popular prediction method for signal peptides, the intrinsic signals that make proteins secretory. The SignalP web server has existed since 1995 and is now in its sixth major version. In this historical account, we (three authors who have taken part in the entire journey plus the first author of the latest version) describe the differences between the versions and discuss the various decisions taken along the way.
Original language | English |
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Title of host publication | Protein Bioinformatics |
Editors | Frédérique Lisacek |
Number of pages | 37 |
Volume | 2836 |
Publication date | 2024 |
Pages | 331-367 |
Chapter | 17 |
DOIs | |
Publication status | Published - 2024 |
Series | Methods in molecular biology (Clifton, N.J.) |
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ISSN | 1064-3745 |
Bibliographical note
Publisher Copyright:
© 2024. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.
- Hidden Markov model, Neural network, Protein language model, Signal peptide
Research areas
ID: 399110217